Xantelasma is a flat benign formation with yellowish color in the form of a slightly elevated plaque. It is located more often on the upper eyelid at the inner corner of the eye. Xantelasma may have single, multiple, or one of the manifestations of xanthomatosis of the skin, in which xantelasm-like plaques are located in other parts of the body.
Diagnosis is based on the appearance. When xantelasma is detected, the lipid spectrum of the blood is examined. If it is detected, the therapy is aimed at correcting the lipid and blood cholesterol content. To eliminate the cosmetic defect, xantelasm is removed.
It mainly affects older people and most often women. A number of authors believe that xantelisma can be considered as a marker of severe atherosclerosis and an increased risk of developing myocardial infarction.
The exact causes of xanthelasma are not known. Xanthomatosis of the skin develops as a result of local deposits of fats in the papillary layer of the dermis. Although xantelases do not differ in their structure from xanthomas, their isolated appearance often fails to detect significant disorders of the metabolism of fat.
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