The National Center for Advancing Translational Sciences defines cold urticaria as a condition that affects the skin directly. They add that the easiest way to diagnosis this condition is based on the presence of certain signs and symptoms. Below you will find the signs and symptoms of cold urticaria as well as the causes and possible treatments for it.
Causes: According to Demetrios Theodoropoulos, MD, DSc, MSc, FACMG, FAAP, with Allergy Associates of La Crosse, the cause of cold urticaria cannot be identified. But the National Organization for Rare Disorders explains that this condition is the most common form of urticaria (hives). The National Center for Advancing Translational Sciences states that cold urticaria is not an inherited condition, but in rare cases has been associated with infectious diseases or blood conditions that include cryoglobulinemia, chronic lymphocytic leukemia, lymphosarcoma, chicken pox, viral hepatitis, and mononucleosis. However, the familial cold urticaria (another form of this condition), has been traced to the long arm of chromosome one (1q40). Chromosomes are found in the nucleus of all body cells that carry the genetic characteristics of each individual. Pairs of human chromosomes are numbered from 1 through 22, with an unequal 23rd pair of X and Y chromosomes for males and two X chromosomes for females.
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